Short version: around Boulder, Botox runs a median of $10 per unit among providers who publish pricing (range $7 to $20). A standard frown-line treatment of about 20 units lands near $140 to $400. In Colorado, injecting is the practice of medicine, but who may do it depends on their own license: physicians and nurse practitioners act on their own authority, while an unlicensed injector acts only as a physician's delegatee.
I pulled the pricing below from the providers' own websites, not from a survey or an industry average. That's worth saying because the single most annoying thing about shopping for injectables around here is that almost nobody will tell you the price before you're in the chair.
What it actually costs around Boulder
Of the 142 providers within an hour of Boulder that offer injectables, exactly 16 publish a per-unit price. That's 11 percent. The rest ask you to book a consultation to find out.
| Measure | Per unit | What a 20-unit area costs |
|---|---|---|
| Lowest published locally | $7 | $140 |
| Median published locally | $10 | $200 |
| Highest published locally | $20 | $400 |
Source: per-unit prices published on the websites of 16 Boulder-area providers, collected July 2026. Prices change; check before you book.
The Dysport price trap
You'll see Dysport advertised at a lower price per unit and reasonably conclude it's the cheaper option. It usually isn't. Dysport is dosed on a different scale, and it takes roughly two and a half to three Dysport units to do the work of one Botox unit.
So a clinic charging $4 per Dysport unit and $12 per Botox unit is charging you about the same for the same result. Ask for the total cost of treating your area, not the per-unit rate. Any provider who won't give you that number is telling you something.
The full conversion table, the onset and duration differences, and how many local providers actually carry each product are in Botox vs Dysport near Boulder.
How many units you actually need
| Area | Typical units | Notes |
|---|---|---|
| Frown lines between the brows | 20 | The FDA-labelled dose. Strong muscles may need more. |
| Forehead lines | 20 | Often treated together with the frown lines. |
| Crow's feet | 24 | Split across both sides, 12 each. |
First-time patients frequently use less, and a good injector will often start conservative and have you back in two weeks. That's a sign of skill, not upselling. It's much easier to add a few units than to wait out a heavy brow for three months.
Who is legally allowed to inject you in Colorado
This is the part most local roundups skip, and most of them get it wrong. I got it wrong here too, until a reader asked me a sharp question about a practice run by a nurse practitioner.
Colorado Medical Board Rule 800 defines a Medical-Aesthetic Service as a cosmetic service that constitutes the practice of medicine, and it names two in particular: injecting any substance into the body, and using a Class IIIb or higher laser, radio-frequency device or intense pulsed light. So yes, injectables and real lasers are medicine in Colorado, not beauty treatments.
What almost everyone then gets wrong, including this site until recently, is who Rule 800 actually applies to. The rule says it in its own introduction:
This Rule does not govern delegation of medical services to physician assistants, anesthesiologist assistants or those individuals regulated by the Board of Nursing.
Rule 800 is about delegation to unlicensed people. Nurses are covered by the Nurse Practice Act. Physician assistants are covered by Rule 400. That changes the picture considerably:
- A physician injects on their own authority.
- A nurse practitioner also acts on their own authority. Colorado gives NPs full practice authority after a mentored prescribing period, with no collaborative agreement and no physician oversight required. An NP-led practice does not need a physician on site delegating to them, and plenty of good local practices are exactly that.
- A physician assistant works under Rule 400, in a collaborative relationship with a physician. Colorado abolished PA supervision in 2023 and replaced it with collaboration.
- A registered nurse or practical nurse works within their scope under the Nurse Practice Act, with appropriate direction.
- An unlicensed person may inject only as a physician's delegatee under Rule 800, if that physician has determined they are qualified by education, training or experience.
- Delegated services cannot be re-delegated. A delegatee may not hand the task to someone else.
So the question I used to think mattered most, "what license does my injector hold," is the wrong question. The better one is under whose authority are they acting, and if that authority is delegated, where is the delegating physician right now?
That second half is worth pressing on, because Rule 800 sets a lower floor than most people would guess. The delegating physician must normally be on the premises and readily available. But where there are specific written protocols and written emergency protocols, they need only be physically present in the state and able to promptly and personally attend to the patient, or to have named a covering physician who is. The required check-in on the delegatee's work is once every two weeks.
Two more things Rule 800 says that rarely come up in a consultation. Prescribing cannot be delegated, which matters because botulinum toxin and dermal fillers are prescription products. And delegated services are supposed to be routine and technical: the rule says a physician should not delegate a service that requires the delegatee to exercise medical judgment.
The off-label clause is the one worth knowing. Rule 800 says off-label use of medications or devices when performing delegated Medical-Aesthetic Services is generally prohibited, unless the delegating physician has specifically authorised that off-label use and it is within generally accepted standards of practice. Several popular filler treatments are off-label, including under-eye and non-surgical nose work. If your injector is acting under delegated authority, that authorisation is supposed to be specific. Which areas are off-label is here.
A 2025 law almost nobody around here is following visibly
This is the part I'd most like you to remember. Colorado passed HB25-1024, the Medical-Aesthetic Services Delegation Disclosures act, which was signed in April 2025 and has been in force since 6 August 2025. It applies to a physician or an advanced practice registered nurse who delegates aesthetic treatment to someone who is not a licensed health-care provider. When that happens, four things are required:
- A highly visible notice at the location giving the delegating licensee's name, their Colorado license number, contact details, and an online address where you can file a complaint with the board.
- That same name and license number posted on the website and on all advertising materials for the unlicensed individual.
- An informed consent form, which you sign, stating in terms that you are receiving services delegated to an unlicensed individual.
- That consent form kept for at least seven years.
So here is a thing you can check in about ten seconds, before you ever pick up the phone. I searched every page we have collected from all 262 providers in this directory. Nine mention a license number at all, and on inspection only a couple are genuine disclosures rather than an address or a phone number that happened to match. Two do it properly and deserve the credit: Jmarie Skin Studio in Longmont names its delegating physician with a Colorado Medical Board license number, and EIR aesthetics in Lafayette names an advanced practice nurse license number.
Be careful how you read that, because I am not accusing anyone of anything. The requirement only bites when the person actually performing your treatment is unlicensed. A practice whose injectors are all nurses or PAs has no notice to post. What the low number tells you is that this information is very hard to find locally, not that most places are breaking the law.
What it does give you is a clean question: is the person treating me licensed, and if not, where is the notice? A practice that can answer that instantly is a practice that has thought about it.
A disclosure you are entitled to, and probably have never been given
Rule 800 requires delegating physicians to make sure delegatees tell you that a delegatee, not the physician, is performing the service. Where the physician is not actively involved in your visit, that disclosure has to include four specific things:
- that what you are receiving is a medical service;
- that the person performing it is not licensed by the state of Colorado, or is acting beyond the scope of their Colorado license;
- that they are doing it under a physician's delegated authority; and
- that the delegating physician is available personally to consult with you, or to evaluate or treat you, in relation to that service.
It has to be documented each time the service is performed, and it can be folded into a consent form. If you have ever had an injectable in Colorado from someone whose license you never established, and you were never told any of that, it is fair to wonder whether the disclosure happened or whether the person injecting simply held a license that put them outside Rule 800 entirely. Both are possible. Asking is reasonable.
One correction worth stating plainly, since this site said otherwise until 27 July 2026: Rule 800 does not require every med spa to have a medical director. It requires a delegating physician, a written agreement, documentation, and the disclosure above, wherever unlicensed delegatees are performing medical services. "We have a medical director" is a weaker signal than it sounds, and it is not the same as "a physician is responsible for your treatment and is reachable today."
None of this makes an NP-led or nurse-led practice worse than a physician-led one. It often makes it clearer, because the person treating you is the person accountable for it. The useful question is not whether there is a medical director. It is who is responsible for this treatment, under what authority, and are they here.
That's why provider credentials and oversight carry 20 percent in how we score, level with reviews and with price transparency.
Worth knowing that this framework applies identically to a dermatology practice and a med spa, which is why the choice between them turns on different things. That comparison is here.
What local patients actually talk about
Across the 137 reviews from the past year that name a toxin by brand, from providers in this area, almost nobody talks about price. They talk about the injector. Specifically, they talk about whether their brows dropped, whether they still look like themselves, and whether the person injecting listened when they said they wanted it subtle.
One review that captures the pattern: "I tend to get heavy brows but not with her. She knows where to inject properly to prevent that."
The practical takeaway: an experienced injector at $14 a unit is a better purchase than an inexperienced one at $8. This is not a commodity, and the cheapest unit price in town is rarely the thing you should optimize for.
What to ask before you book
- What's the total cost for my areas, all in?
- Who's injecting, and what license do they hold?
- Are they injecting on their own authority, or under a physician's delegation? If delegated, who is that physician and are they reachable today?
- How many units are you recommending, and why that number?
- Do you do a two-week follow-up if it needs adjusting, and is it included?
Highest-scoring local providers offering injectables
From the 142 in our directory, scored on the published rubric:
- Rejuvenate MedSpa, Golden. Score 98.
- 4Ever Young Med Spa, Arvada. Score 97.
- Youthbar, Boulder. Score 96.
- Rinnova Skin & Body, Boulder. Score 96.
- Evolution Dermatology, Boulder. Score 96.
- Clearview Dermatology, Arvada. Score 96.
If filler is on the table at the same appointment
It very often is, because toxin and filler get sold together and the rebate programmes reward carrying both. Treat it as a separate decision with separate homework. The pricing is more opaque, the products vary far more than toxins do, and only one of the four filler materials can be dissolved if you don't like it. That's in the dermal filler guide.
A word about what this is
I'm a medical technologist, not a physician, and none of this is medical advice. Botulinum toxin is a prescription drug with real contraindications, and whether it's appropriate for you is a conversation with a licensed clinician who can examine you. What I can tell you is what it costs here, who's legally allowed to do it, and which local providers score well on evidence you can verify yourself.